Table 1.
Comparisons of clinical characteristics of gram-negative bacteraemia between the follow-up blood culture (FUBC) and no-FUBC groups
| FUBC-drawn (n = 1276) | No FUBC-drawn (n = 205) | p-value | |
|---|---|---|---|
| Age, years (± SD) | 68.85 (± 14.27) | 69.2 (± 14.13) | 0.744 |
| Sex (M) | 628 (49.2%) | 117 (57.1%) | 0.042* |
| Body weight (kg) | 59.90 (± 11.56) | 59.24 (± 12.62) | 0.533 |
| Comorbidity | |||
| DM | 404 (31.7%) | 70 (34.1%) | 0.519 |
| Liver cirrhosis | 95 (7.4%) | 17 (8.3%) | 0.776 |
| ESRD on HD | 2 (1.0%) | 35 (2.7%) | 0.154 |
| ESRD on PD | 6 (0.5%) | 0 (0.0%) | 1.000 |
| Rheumatic disease | 18 (1.4%) | 1 (0.5%) | 0.500 |
| Haematologic malignancy | 136 (10.7%) | 7 (3.4%) | 0.001* |
| Solid malignancy | 361 (28.4%) | 60 (29.4%) | 0.802 |
| Solid organ transplantation | 34 (2.7%) | 5 (2.4%) | 1.000 |
| Bone marrow transplantation | 28 (2.2%) | 1 (0.5%) | 0.167 |
| Intravascular device | 308 (24.1%) | 19 (9.3%) | 0.000* |
| Neutropenia | 127 (10.0%) | 6 (2.9%) | 0.002* |
| High-dose steroid | 24 (1.9%) | 1 (0.5%) | 0.239 |
| Microorganism | |||
| Escherichia coli | 722 (56.6%) | 113 (55.1%) | 0.705 |
| Klebsiella pneumoniae | 250 (19.6%) | 45 (22.0%) | 0.451 |
| Pseudomonas aeruginosa | 62 (4.9%) | 7 (3.4%) | 0.384 |
| AmpC-encoded Enterobacteriaceaea | 100 (7.8%) | 21 (10.2%) | 0.237 |
| Acinetobacter baumannii | 24 (1.9%) | 1 (0.5%) | 0.239 |
| ESBL-producing | 313 (24.5%) | 32 (15.6%) | 0.006* |
| Other gram-negative | 110 (8.6%) | 17 (8.3%) | 0.895 |
| PBSI | 50 (3.9%) | 8 (3.9%) | 1.000 |
| Hospital onset | 328 (25.7%) | 53 (25.9%) | 1.000 |
| Site of infection | |||
| Urinary genital tract | 502 (39.3%) | 71 (34.6%) | 0.217 |
| Liver abscess | 56 (4.4%) | 7 (3.4%) | 0.583 |
| Biliary | 303 (23.7%) | 86 (42.0%) | 0.000* |
| Intra-abdominal | 135 (10.6%) | 18 (8.8%) | 0.462 |
| Respiratory | 56 (4.4%) | 5 (2.4%) | 0.255 |
| SSTI | 13 (1.0%) | 1 (0.5%) | 0.707 |
| Catheter-related | 40 (3.1%) | 2 (1.0%) | 0.109 |
| Bone and joint infection | 12 (0.9%) | 1 (0.5%) | 1.000 |
| Cardiovascular | 3 (0.2%) | 0 (0.0%) | 1.000 |
| CNS infection | 3 (0.2%) | 0 (0.0%) | 1.000 |
| Primary bacteraemia | 143 (11.2%) | 10 (4.9%) | 0.006* |
| In-hospital mortality | 87 (6.8%) | 18 (8.8%) | 0.379 |
SD Standard deviation, M Male, DM Diabetes mellitus, ESRD End-stage renal disease, HD Haemodialysis, PD Peritoneal dialysis, ESBL Extended-spectrum beta-lactamase, PBSI Polymicrobial bloodstream infection, SSTI Skin and soft tissue infection, CNS Central nervous system
aAmpC-encoded Enterobacteriaceae includes Serratia marcescens, Providencia stuartii, Proteus vulgaris, Citrobacter spp., Enterobacter spp., and Morganella morganii
*p < 0.05