Table 1.

Resistance pattern of the MDR-TB strain

Drug	Phenotypical susceptibility testing	Associated mutations
Rifampicin/Rifabutin	Resistant	rpoB gene: mutation S531L
Isoniazid	Resistant	katG gene: mutation S315T
Isoniazid/Ethionamide	Resistant	inhA promotor: mutation T-8C
Ethambutol	Resistant	embB gene: mutation M306I
Pyrazinamide	Resistant	pncA gene: mutation T47A
Levofloxacin	Resistant (0,5 mg/l)	gyrA gene: wild type gyrB gene: mutation E540N
	Susceptible (1 mg/l)
Moxifloxacin	Resistant (0,25 mg/l)
	Susceptible (1 mg/l)
Aminoglycosides	Susceptible	rrs gene: wild type eis gene: wild type
Cycloserine	Susceptible
Para-aminosalicylic acid (PAS)	Susceptible
Linezolid	Susceptible
Bedaquiline	Susceptible
Clofazimine	Susceptible
Delamanid	Susceptible