Figure 2.

Relative expression of miR-130a, miR-25 and miR-191* in irradiated A549 in vitro and in vivo. (A) Scatter plots of miR-130a, miR-25 and miR-191* expression at various time-points after 2- or 4-Gy irradiation of A549 cells. (B) Relative expression of miR-130a, miR-25 and miR-191* in the lung and serum of nude mice 3, 6 and 10 weeks after injection with A549 cells. (C) The relative expression levels of miR-130a, miR-25 and miR-191* in the lung and serum of nude mice 10 weeks after injection with A549 cells irradiated with 0-, 2- and 4-Gy X-ray. Reverse transcription-quantitative PCR was performed in triplicate, and each experiment was repeated ≥3 times. The dotted line represents the level of the control group. *P<0.05 and **P<0.01 vs. control. miR, microRNA.