Table I.

General information and clinical characteristics of patients with NSCLC, and statistical differences of miR expression levels in patients with different clinical characteristics.

		P-value
Category	n (%)	miR-130a	miR-25	miR-191-3p
Sex
Male	58 (69)	0.477	0.180	0.102
Female	26 (31)
Age, years
<60	36 (43)	0.762	0.035a	0.058
≥60	48 (57)
Smoking status
Yes	42 (50)	0.254	0.188	0.115
No	42 (50)
Radiotherapy
Yes	33 (39)	0.004b	0.003b	0.047a
No	51 (61)
Histological type
Adenocarcinoma	46 (55)	0.584	0.013a	0.006b
Squamous cell carcinoma	38 (45)
Lymph node metastasis
Yes	66 (79)	0.887	0.200	0.639
No	18 (21)
Extracranial metastasis
Yes	67 (80)	0.777	0.534	0.773
No	17 (20)
BM
Yes	22 (26)	0.559	0.542	0.535
No	62 (74)
No. of BM
0	62 (74)	0.529	0.871	0.670
1	5 (6)
≥2	17 (20)
Maximum diameter of BM, cm
0	62 (74)	0.448	0.305	0.121
≤2	11 (13)
>2	11 (13)
TNM T stage
T1	3 (4)	0.378	0.733	0.157
T2	0 (0)
T3	5 (6)
T4	76 (90)
N stage
N0	18 (21)	0.235	0.222	0.234
N1	17 (20)
N2	24 (29)
N3	25 (30)
Survival status
Death	26 (31)	0.054	0.016a	0.033a
Survival	58 (69)
ECOG performance status
1	47 (56)	0.836	0.989	0.935
2	37 (44)

^aP<0.05

^bP<0.01 determined using the Mann-Whitney U test. BM, brain metastasis; TNM, Tumor-Node-Metastasis; N, Node; ECOG, Eastern Cooperative Oncology Group.