Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Jul 6;3(1):67–90. doi: 10.1089/nsm.2020.0004

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Blandine Comte et al. 2020; Published by Mary Ann Liebert, Inc.

This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

FIG. 1. — Medical knowledge gaps and the ground-breaking nature of Network and Systems Medicine. (A) Time course of most chronic diseases without knowing the causal mechanism. Diagnosis relies on signs and symptoms pointing to (B) specific organs. Therapy focuses on achieving patient-relevant outcomes only in (C) a small fraction (green) of patients.⁵ (D) Network and Systems Medicine aims at defining and diagnosing a disease mechanistically, and at treating it with higher precision, based on (E) mechanism-based diagnostics and therapeutics (i.e., theranostics).