Table 6.
The Positive and Negative Predictive Values From Image Evaluation of RW-ROP at Various Prevalence
| Person-Level Analysis* | Eye-Level Analysis† | |||
|---|---|---|---|---|
| Assumed Prevalence of RW-ROP | Positive Predictive Value (95% CI)* | Negative Predictive Value (95% CI)* | Positive Predictive Value (95% CI) | Negative Predictive Value (95% CI) |
| 5% | 26.5% (16.8–39.1%) | 99.8% (98.6–99.9%) | 25.4% (18.3–36.0%) | 99.1% (98.3–99.6%) |
| 10% | 43.2% (29.9–57.6%) | 98.6% (97.0–99.9%) | 41.3% (31.9–54.5%) | 98.0% (96.5–99.3%) |
| 15% | 54.7% (40.4–68.3%) | 99.3% (95.3–99.9%) | 52.8% (42.5–65.8%) | 96.9% (94.6–98.8%) |
| 20% | 63.1% (49.0–75.3%) | 99.0% (93.5–99.9%) | 61.3% (51.7–72.7%) | 95.7% (92.4–98.3%) |
| 25% | 69.5% (56.1–80.3%) | 98.7% (91.6–99.8%) | 68.3% (57.8–78.2%) | 94.3% (90.0–97.8%) |
| 30% | 74.6% (62.2–84.0%) | 98.3% (89.4–99.8%) | 73.1% (64.7–82.4%) | 92.7% (87.9–97.1%) |
*
Predictive values were calculated by using sensitivity of 96.6% and specificity of 85.9% from the per-infant analysis in Table 4, their 95% CIs were calculated using the logit transformation.
†
Predictive values were calculated by using sensitivity of 83.7% and specificity of 86.8% from the eye-level analysis in Table 5, and their 95% CIs were calculated using the cluster bootstrap.