Table 1.
Groups | TTC | WB | BT | IF | Death | Mortality (%) |
---|---|---|---|---|---|---|
Sham | 6 | 6 | 0 | 0 | 0 | 0 (0/12) |
1 h MCAO/R 24 h + IgG isotype | 6 | 6 | 0 | 0 | 0 | 0 (0/12) |
1 h MCAO/R 24 h + IL-17A-mAb | 6 | 6 | 0 | 0 | 1 | 7.7 (1/13) |
Sham | 0 | 0 | 10 | 6 | 0 | 0 (0/10) |
1 h MCAO/R 3 d + IgG isotype | 0 | 0 | 10 | 6 | 1 | 9.1 (1/11) |
1 h MCAO/R 3 d + IL-17A-mAb | 0 | 0 | 10 | 6 | 2 | 16.7 (2/12) |
Total (70) | 18 | 18 | 30 | 4 | 5.7 (4/70) |
MCAO, middle cerebral artery occlusion; R, reperfusion; TTC, triphenyl tetrazolium chloride; WB, Western blot; IF, immunofluorescent staining; BT, behavior test. The numbers of IF were included in the BT.