Table 1.
Concordance between select ICD-10-AM codes for cirrhosis or cirrhosis-related complications and medical chart review
| ICD-10-AM code | n with condition on clinical review | n with code | PPV (95% CI) |
NPV (95% CI) |
κ | |
| Cirrhosis | 413 | |||||
| K70.3 Alcoholic cirrhosis of liver | 193 | 0.97 (0.95 to 0.99) | 0.35 (0.30 to 0.40) | |||
| K74.4 Secondary biliary cirrhosis* | 12 | 1.00 | 0.24 (0.21 to 0.28) | |||
| K74.5 Biliary cirrhosis, unspecified | 6 | 0.67 (0.28 to 0.94) | 0.23 (0.20 to 0.27) | |||
| K74.6 Other and unspecified cirrhosis of liver | 169 | 0.96 (0.93 to 0.99) | 0.33 (0.28 to 0.38) | |||
| Grouped† K70.3, K74.4, K74.5, K74.6 (Algorithm #1) | 349 | 0.96 (0.94 to 0.98) | 0.60 (0.53 to 0.67) | 0.606 | ||
| Cirrhosis-related complications | ||||||
| HCC | C22.0 Liver cell carcinoma | 82 | 74 | 0.97 (0.92 to 1.00) | 0.98 (0.96 to 0.99) | 0.910 |
| Ascites | R18 Ascites | 244 | 155 | 0.97 (0.94 to 0.99) | 0.76 (0.71 to 0.80) | 0.625 |
| Varices | Grouped† varices (I85.0, I85.9, I86.4, I98.2, I98.3) | 243 | 157 | 0.95 (0.91 to 0.98) | 0.76 (0.71 to 0.80) | 0.606 |
| I85.0 Oesophageal varices with bleeding | 27 | 1.00 | 0.58 (0.54 to 0.62) | |||
| I85.9 Oesophageal varices without bleeding | 32 | 0.88 (0.73 to 0.96) | 0.58 (0.53 to 0.62) | |||
| I86.4 Gastric varices | 41 | 0.93 (0.82 to 0.98) | 0.59 (0.55 to 0.63) | |||
| I98.2 Oesophageal varices without bleeding in diseases classified elsewhere | 52 | 0.94 (0.86 to 0.99) | 0.60 (0.56 to 0.65) | |||
| I98.3 Oesophageal varices with bleeding in diseases classified elsewhere | 43 | 1.00 | 0.60 (0.55 to 0.64) | |||
| SBP | Grouped† SBP (K65.0, K65.9) | 46 | 47 | 0.75 (0.61 to 0.85) | 0.98 (0.96 to 0.99) | 0.729 |
| K65.0 Acute peritonitis | 24 | 0.63 (0.43 to 0.80) | 0.94 (0.92 to 0.96) | |||
| K65.9 Peritonitis, unspecified | 23 | 0.87 (0.70 to 0.97) | 0.95 (0.93 to 0.97) | |||
| HE | Grouped† HE (G31.2, G93.4) | 142 | 64 | 0.55 (0.43 to 0.67) | 0.78 (0.74 to 0.81) | 0.211 |
| G31.2 Degeneration of nervous system due to alcohol | 30 | 0.37 (0.21 to 0.55) | 0.74 (0.70 to 0.78) | |||
| G93.4 Encephalopathy, unspecified | 34 | 0.71 (0.54 to 0.84) | 0.77 (0.73 to 0.80) | |||
*ICD-10-AM code for primary biliary cirrhosis/cholangitis (K74.3) not shown as this code may be associated with early stage liver disease, not cirrhosis
†‘Grouped’ codes indicate the presence of ≥1 code during an encounter.
HCC, hepatocellular carcinoma; HE, hepatic encephalopathy; ICD-10-AM, Australian Modification of the 10th revision of the International Classification of Diseases; NPV, negative predictive value; PPV, positive predictive value; SBP, spontaneous bacterial peritonitis.