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. 2020 Sep 4;10:1544. doi: 10.3389/fonc.2020.01544

Table 1.

Patient clinical data.

Patient Gender Age BCR-ABL (%) Breakpoint
Untreated group
1 M 61 92 b2a2
2 M 52 100 b2a2
3 M 35 100 b2a2
4 F 54 100 b2a2
5 M 46 73 b3a2
6 M 72 100 b2a2
7 F 80 100 b3a2
8 M 67 100 b3a2
9 M 59 40 b2a2
10 M 60 82 b2+b3
11 F 52 100 b3a2
12 M 37 100 b3a2
13 F 53 100 b3a2
14 M 72 100 b3a2
Patients Gender Age HSCT indication Source DAT BCR-ABL (%) Breakpoint Mutation Follow up
Hematopoietic stem cell transplantation group
1 M 37 Disease progression BM 224 1.60 b2a2 Absence Relapsed
2 F 44 Failed therapy BM 231 1,20 b3a2 Absence Relapsed
3 F 03 Disease progression BM 208 0.20 b3a2 _ Relapsed
4 F 63 FC BM 1569 0.20 b3a2 Absence Relapsed
5 M 37 Failed therapy BM 110 0.50 b2a2 _ Relapsed
6 M 43 FC BM 2450 0.30 b3a2 _ MMR
7 M 48 Disease progression PBSC 80 0.75 b3a2 Absence MMR
8 M 35 Failed therapy BM 2352 0.03 b3a2 Absence Relapsed
9 M 42 Failed therapy PBSC 3561 0.01 b2a2 _ Relapsed
10 F 42 Disease progression PBSC 3708 0.01 b3a2 _ MMR
11 F 56 FC BM 3932 0.03 b2a2 Absence MMR
12 M 32 FC PBSC 3242 0.08 b2a2 _ Relapsed
13 M 21 FC BM 1949 0.30 b3a2 Absence Relapsed
14 M 58 Disease progression BM 41 0.02 b2a2 _ MMR

DAT, days after transplantation; BM, bone marrow; PBSC, peripheral blood stem cell; (-), BCR-ABL mutation test was not performed; MMR, Major molecular response (BCR-ABL1 transcript level ≤ 0.1%).