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Expression of key bile acid homeostasis genes in pregnant females. A: mRNA expression of genes regulating bile acid synthesis and transport in the liver. B: mRNA expression of genes regulating bile acid synthesis and transport in the terminal ileum. Data are presented as means ± SE; n = 4–6 mice. *P ≤ 0.05 in comparisons vs. normal chow diet (NC) and obeticholic acid (OCA groups); ‡P ≤ 0.05 in comparisons vs. all groups. CA, cholic acid; D18, day 18 pregnant.
