Table 1. Baseline characteristics and RDN ablation parameters.
| Index | Standard treatment | Intensive treatment | P |
|---|---|---|---|
| n (%) | 21 (50.0) | 21 (50.0) | 1.00 |
| Age, y | 61.8 ± 13.3 | 62.7 ± 12.8 | .713 |
| Sex (male), n(%) | 16 (38.1) | 15 (35.7) | .726 |
| HR (bpm, ) | 79.7 ± 10.0 | 82.0 ± 17.0 | .612 |
| Medical history n(%) | |||
| CAD | 6 (14.4) | 10 (24.0) | .170 |
| 2-DM | 9 (23.8) | 9 (23.8) | .622 |
| Atrial fibrillation | 3 (7.1) | 0 (0.0) | .116 |
| Hyperlipidemia | 3 (7.1) | 4 (9.5) | .500 |
| Stroke | 4 (9.5) | 1 (2.4) | .172 |
| Type of antihypertensive medication n(%) | |||
| RAAS Blockers | 20 (48.0) | 13 (31.2) | .010 |
| β-Blocker | 18 (43.2) | 14 (33.6) | .139 |
| Ca2+-Blocker | 16 (38.4) | 15 (36) | .500 |
| Diuretics | 21 (50.0) | 21 (50.0) | 1.00 |
| Ambulatory BP (mm Hg, ) | |||
| SBP | 155.9 ± 23.2 | 168.6 ± 28.4 | .107 |
| DBP | 87.4 ± 12.1 | 93.9 ± 14.8 | .092 |
| Ablation points | 6.2 ± 0.8 | 11.0 ± 2.0 | .000 |
| Ablation impedance (Ω, ) | |||
| Initial | 177.9 ± 26.6 | 190.1 ± 22.4 | .115 |
| Lowest | 159.0 ± 21.9 | 167.2 ± 18.1 | .193 |
| Creatinine (mg/dL, ) | 102.1 ± 47.9 | 135.7 ± 193.5 | .455 |
| eGFR [mL/min/1.73m2, ] | 73.6 ± 24.1 | 71.8 ± 28.0 | .829 |
| Glucose (mg/Dl, ) | 6.5 ± 2.4 | 5.5 ± 2.0 | .135 |
| AST (U/L, ) | 22.2 ± 9.2 | 36.9 ± 15.1 | .339 |
| ALT (U/L, ) | 20.5 ± 14.32 | 38.6 ± 18.8 | .351 |
| Hb (g/L, ) | 133.3 ± 16.2 | 141.1 ± 26.5 | .260 |
| BNP (pg/mL, ) | 596.9 ± 220.2 | 422.3 ± 146.7 | .506 |
Notes.
Abbreviations
- F
- female
- M
- male
- CAD
- coronary artery disease
- DM
- diabetes mellitus
- RAAS
- renin-angiotensin-aldosterone system
- Ca 2+
- calcium Data are given as %
- SBP
- Systolic blood pressure
- DBP
- Diastolic blood pressure
- AST
- aspartate aminotransferase
- ALT
- Alanine aminotransferase
- Hb
- hemoglobin
- BNP
- Brain natriuretic peptide