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. 2020 Sep 4;11:1269. doi: 10.3389/fphar.2020.01269

Figure 4.

Figure 4

Effects of anti-IL 17 treatment on TGF-β and neutrophils in BALF. Panel A shows the expression of positive cells for TGF-β in the pulmonary vessels and Panel B shows the number of neutrophil cells in the bronchoalveolar lavage fluid. The values represent the mean ± SE of TGF-β and neutrophils for all experimental groups. The differences were considered significant when p < 0.05. *p < 0.05 vs. SAL group; **p < 0.05 vs. OVA and OVA–LPS groups. #p < 0.05 vs. OVA group. Photomicrograph pulmonary vessels measuring TGF-β. The animals exposed to only ovalbumin and ovalbumin plus LPS (OVA and OVA–LPS groups) presented prominent increases in the numbers of positive cells, compared with the control animals (SAL group). Anti-IL-17 treatment in the OVA anti-IL-17 and OVA–LPS anti-IL-17 groups ameliorated all increases in these markers. The red arrows indicate the positive cells for TGF-β.