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. 2020 Sep 4;11:529976. doi: 10.3389/fphar.2020.529976

Figure 4.

Figure 4

Effect of pharmacological modulation of AA cascade on Caco-2 cell growth induced by oleic and EPA. Caco-2 cells were incubated without FBS for 48 h with oleic or EPA at 10 µM in presence or absence of ketoprofen (Kp, 5 µM), AH23848 (AH23, 20 nM), SC19220 (SC19, 60 nM), baicalein (Bai, 25 µM), MK886 (MK8, 10 µM), U75302 (U75, 5 µM), LY25283 (LY25, 25 µM), MK571 (MK5, 25 µM), or LY171883 (LY17, 25 µM) and cells were counted. Results are expressed as mean ± SEM (n = 8–16). *P < 0.05 vs. control group (white bar, cells cultured without FBS), #P < 0.05 versus oleic acid (10 µM), and §P < 0.05 versus EPA (10 µM).