TABLE 2.

Sensitivity and Specificity of Altered Serum Proteins in IBD: ROC Analysis

	Protein	AUC	95% CI	P *
Elevated, serum	CXCL9	0.864	0.744-0.984	<0.001
	CSF1	0.848	0.720-0.975	<0.001
	IL-17A	0.845	0.709-0.982	<0.001
	OSM	0.840	0.723-0.958	<0.001
	IL-7	0.833	0.704-0.962	<0.001
	IL-10	0.836	0.710-0.961	<0.001
	MMP-10	0.831	0.707-0.955	<0.001
	CCL23	0.817	0.672-0.961	0.001
	CCL11	0.812	0.675-0.949	0.001
	IL-6	0.810	0.677-0.942	0.001
	HGF	0.786	0.638-0.934	0.002
	TGF-α	0.786	0.638-0.934	0.002
	CXCL11	0.783	0.638-0.929	0.002
	CXCL1	0.757	0.599-0.915	0.005
	MCP-3	0.745	0.594-0.897	0.007
	VEGFA	0.738	0.586-0.890	0.009
	OPG	0.738	0.569-0.907	0.009
	MMP-1	0.729	0.576-0.881	0.012
	CD8A	0.724	0.564-0.883	0.014
	IL-17C	0.721	0.564-0.879	0.015
	IL-24	0.720	0.562-0.878	0.016
Elevated, saliva	IL-6	0.886	0.776-1.000	<0.001
	MMP-10	0.778	0.620-0.935	0.003
Decreased, serum	AXIN1	0.745	0.583-0.907	0.007
	SIRT1	0.745	0.589-0.901	0.007
	STA1A	0.745	0.595-0.895	0.007
	CASP-8	0.729	0.572-0.885	0.012

*ROC, asymptotic significance.

AUC indicates area under the curve; ROC, receiver operating characteristics.