TABLE 2.
Differential Expression of 7 Serum miRNAs in the Discovery Cohort, Separated into Responder and Nonresponder Groups and Indicating the Direction of Change from Pre- to Post-treatment
Responders | Nonresponders | |||||
---|---|---|---|---|---|---|
miR | ↑ or ↓ | P | Rq | ↑ or ↓ | P | Rq |
193b | ↑ | <0.001 | 7.81 | ↑ | Ns | 15.1 |
636 | ↑ | 0.01 | 6.71 | ↑ | Ns | 3.28 |
454 | ↓ | 0.02 | 0.11 | n.d. | Ns | 1 |
126 | ↓ | 0.02 | 0.32 | n.d. | Ns | 1 |
26b | ↓ | 0.02 | 0.11 | n.d. | Ns | 1 |
let7c | ↓ | 0.02 | 0.14 | ↑ | Ns | 6.52 |
26a | ↓ | 0.04 | 0.16 | ↓ | Ns | 0.04 |
Abbreviations: Rq, relative quantification; n.d., no difference; Ns, not significant; P ≤ 0.05 significant.