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. 2020 Sep 8;16(9):e1008799. doi: 10.1371/journal.ppat.1008799

Fig 6. Immune suppression by Pf SPZ stimulated macrophages.

Fig 6

A. Experimental setup. Peptide stimulated MoDCs are co-cultured with a peptide specific CD8+ T cell clone in the presence or absence of parasite or control stimulated MoMϕs (information in materials and methods). B. CD8 + cell phenotype after overnight co-culture with MoDCs and MoMϕs. Intracellular IFNγ, activation marker CD137 and Perforin expression. Analysis using Wilcoxon test, N = 4, 8 donors. #: P = <0.05 compared to medium control. *: P = <0.05, **: P = <0.005. C. Representative cytometry plots showing percentage of IFNγ+ CD8 + T cells.