Table 5. Percentages of net products meeting optimal WHO bioefficacy criteria by time point.
| Net product | WHO cone test | WHO tunnel test | Overall (cone + tunnel) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| 10 months | 22 months | 36 months | 10 months | 22 months | 36 months | 10 months | 22 months | 36 months | |
| Olyset | 4 | 8 | 14 | 72 | 78 | 71 | 73 | 79 | 75 |
| (1, 14) | (2, 20) | (5, 27) | (57, 84) | (62, 89) | (54, 85) | (58, 85) | (65, 90) | (60, 87) | |
| [2/48] | [4/48] | [6/44] | [33/46] | [34/44] | [27/38] | [35/48] | [38/48] | [33/44] | |
| PermaNet | 98 | 92 | 73 | 100 | 50 | 46 | 100 | 96 | 85 |
| (89, 100) | (80, 98) | (58, 85) | (3, 100) | (7, 93) | (19, 75) | (92, 100) | (85, 99) | (72, 94) | |
| [46/47] | [44/48] | [35/48] | [1/1] | [2/4] | [6/13] | [47/47] | [46/48] | [41/48] | |
| NetProtect | 100 | 100 | 73 | n/a | n/a | 85 | 100 | 100 | 96 |
| (92, 100) | (93, 100) | (58, 85) | (55, 98) | (92, 100) | (93, 100) | (86, 99) | |||
| [47/47] | [48/48] | [35/48] | [11/13] | [47/47] | [48/48] | [46/48] | |||
| <0.001* | <0.001* | 0.017* | |||||||
95% confidence intervals in parentheses. Numbers passing/numbers tested in square brackets [n/N]. Nets are tested by cone test, and those that fail WHO optimal insecticide effectiveness criteria of ≥95% knock-down after 60 minutes or ≥80% 24-hour mortality are then further tested by tunnel test. Optimal criteria for the tunnel test are ≥80% 24-hour mortality or ≥90% blood feeding inhibition. Overall pass (cone and tunnel) is based on a net achieving 1 or more of these 4 criteria.
*p-Value for the comparison between the 3 nets. For the differences between Olyset and PermaNet, the p-values were <0.001, 0.014, and 0.208 at 10, 22, and 36 months, respectively. For the differences between Olyset and NetProtect, the p-values were <0.001, <0.001, and 0.004 at 10, 22, and 36 months, respectively. For the differences between PermaNet and NetProtect, the p-values were 1.0, 0.153, and 0.080 at 10, 22, and 36 months, respectively.