Table 5. Diagnostic accuracy at each specific cut-point in distinguishing mild TBI patients with positive CT findings from negative CT findings and in distinguishing patients who required neurosurgical intervention from patients who did not.
At & above cut-point | Below cut-point | Sensitivity (95%CI) | Specificity (95%CI) | |||
---|---|---|---|---|---|---|
n | (%) | n | (%) | |||
Positive CT findings | ||||||
Model-based score (cut-point 2) | ≥2 | <2 | ||||
Positive CT findings | 242 | (99.2) | 2 | (0.8) | 99.2 | 8.2 |
Negative CT findings | 845 | (91.9) | 75 | (8.2) | (97.1,99.9) | (6.5,10.1) |
Clinical-based score (cut-point 2) | ≥2 | <2 | ||||
Positive CT findings | 239 | (98.0) | 5 | (2.1) | 98.0 | 16.2 |
Negative CT findings | 771 | (83.8) | 149 | (16.2) | (95.3,99.3) | (13.9,18.7) |
Canadian CT Head Rule | Presence | Absence | ||||
Positive CT findings | 214 | (87.7) | 30 | (12.3) | 87.7 | 22.7 |
Negative CT findings | 711 | (77.3) | 209 | (22.7) | (82.9,91.5) | (20.0,25.6) |
Surgical intervention required | ||||||
Model-based score (cut-point 7) | ≥7 | <7 | ||||
Surgical intervention required | 57 | (100) | 0 | (0) | 100 | 33.2 |
No surgical intervention required | 739 | (66.8) | 368 | (33.2) | (93.7,100) | (30.5,36.1) |
Clinical-based score (cut-point 3) | ≥3 | <3 | ||||
Surgical intervention required | 57 | (100) | 0 | (0) | 100 | 28.3 |
No surgical intervention required | 794 | (71.7) | 313 | (28.3) | (93.7) | (25.6,31.0) |
Canadian CT Head Rule | Presence | Absence | ||||
Surgical intervention required | 54 | (94.7) | 3 | (5.3) | 94.7 | 21.3 |
No surgical intervention required | 871 | (78.7) | 236 | (21.3) | (85.4,98.9) | (18.9,23.9) |
CT ordering proportion | ||||||
Model-based score (cut-point 7) | 796 | (68.4) | ||||
Clinical-based score (cut-point 3) | 851 | (73.1) | ||||
Canadian CT Head Rule | 925 | (79.5) |
Comparison of CT ordering proportions between our newly-derived models and the classic CCHR.
Abbreviations: CI, confidence interval; CT, computed tomography.