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. 2020 Sep 18;15(9):e0239082. doi: 10.1371/journal.pone.0239082

Table 5. Diagnostic accuracy at each specific cut-point in distinguishing mild TBI patients with positive CT findings from negative CT findings and in distinguishing patients who required neurosurgical intervention from patients who did not.

At & above cut-point Below cut-point Sensitivity (95%CI) Specificity (95%CI)
n (%) n (%)
Positive CT findings
Model-based score (cut-point 2) ≥2 <2
    Positive CT findings 242 (99.2) 2 (0.8) 99.2 8.2
    Negative CT findings 845 (91.9) 75 (8.2) (97.1,99.9) (6.5,10.1)
Clinical-based score (cut-point 2) ≥2 <2
    Positive CT findings 239 (98.0) 5 (2.1) 98.0 16.2
    Negative CT findings 771 (83.8) 149 (16.2) (95.3,99.3) (13.9,18.7)
Canadian CT Head Rule Presence Absence
    Positive CT findings 214 (87.7) 30 (12.3) 87.7 22.7
    Negative CT findings 711 (77.3) 209 (22.7) (82.9,91.5) (20.0,25.6)
Surgical intervention required
Model-based score (cut-point 7) ≥7 <7
    Surgical intervention required 57 (100) 0 (0) 100 33.2
    No surgical intervention required 739 (66.8) 368 (33.2) (93.7,100) (30.5,36.1)
Clinical-based score (cut-point 3) ≥3 <3
    Surgical intervention required 57 (100) 0 (0) 100 28.3
    No surgical intervention required 794 (71.7) 313 (28.3) (93.7) (25.6,31.0)
Canadian CT Head Rule Presence Absence
    Surgical intervention required 54 (94.7) 3 (5.3) 94.7 21.3
    No surgical intervention required 871 (78.7) 236 (21.3) (85.4,98.9) (18.9,23.9)
CT ordering proportion
    Model-based score (cut-point 7) 796 (68.4)
    Clinical-based score (cut-point 3) 851 (73.1)
    Canadian CT Head Rule 925 (79.5)

Comparison of CT ordering proportions between our newly-derived models and the classic CCHR.

Abbreviations: CI, confidence interval; CT, computed tomography.