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. Author manuscript; available in PMC: 2020 Sep 18.
Published in final edited form as: Regul Toxicol Pharmacol. 2018 Dec 15;102:53–64. doi: 10.1016/j.yrtph.2018.12.007

Table 4.

Summary of analysis where at least one of the methods generates an out-of-domain result.

Statistic-based result Expert rule-based result Count Percentage of results that were experimentally identified Ames mutagens
Out-of-domain Positive 296 36.2%
Out-of-domain Indeterminate 78 28.2%
Out-of-domain Out-of-domain 1558 11.8%
Out-of-domain Negative 2027 11.8%