FIGURE 4.

An electromicrograph of the ovarian tissues from (a) control group showing that the zona pellucida (ZP) surrounding the oocytes were uniform and integral with the adjacent follicular cells with scattered mitochondria in the cytoplasm of the oocytes; (b) DHEA group showing marked degeneration in the zona pellucida with enlargement of the perivitelline space; (c) DHEA + CMC group showing a large number of apoptotic granulosa cells (GC) spilling in the antrum; (d) DHEA + Telmisartan group showing granulosa cells (GC) with apparently normal euchromatic nuclei and typical steroid‐expressing cell characteristics of the theca cells (TC); (e) DHEA + Fish oil group showing significant decrease in the degeneration of the zona pellucida with minimal apoptosis of the granulose cells; and (f) DHEA + Telmisartan +Fish oil group showing uniform zona pellucida with scattered mitochondria in the cytoplasm of the oocytes. Theca cells exhibited typical steroid‐expressing cell characteristics with lipid droplet content in the follicles with apparently normal granulose cells