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. Author manuscript; available in PMC: 2020 Sep 18.
Published in final edited form as: Am J Surg Pathol. 2018 Mar;42(3):293–305. doi: 10.1097/PAS.0000000000000985

FIGURE 3.

FIGURE 3.

Nodular sclerosis Hodgkin lymphoma-like (NSHL-like) pattern (case 4). A, Lymphomatous nodule surrounded by sclerotic bands resembling NSHL (hematoxylin and eosin). B, The birefringent collagen is highlighted with polarized light. C, The cellular nodule is composed of a polymorphic infiltrate of small lymphocytes, histiocytes, eosinophils, and scattered large Hodgkin and Reed-Sternberg-like cells (hematoxylin and eosin). D, Immunohistochemistry for CD30 highlights the large neoplastic cells, mimicking CHL (anti-CD30 immunohistochemistry with hematoxylin counterstain).