TABLE 3.

Pathologic Features of Patients With BI-ALCL and LNI (n = 14)

Case No.	References	Specimen Type	LN maximum Dimension (mm)	Tumor Burden (%)	Infiltration Pattern
1	Aladily11	Excision	20	70	S, P, I, D
2	Alobeid et al16	Excision	11.8	5	S, P, I
3	Aladily11	Excision	25	5	S, P, I
4	Clemens et al5	Dissection	40	60	S, P, I, D
5	Miranda et al3	Excision	17	5	HL-like
6	George17	Excision	8.9	30	S, P, I
7	Estes et al18	Excision	51	10	S
8	Miranda et al3	Dissection	13	30	S, I, D, NSHL-like
9	Unpublished	Excision	NA	1	S
10	Clemens et al5	Dissection	21	95	S, P, I, D
11	Acevedo-Banez et al19	Needle bx	12	20	S, I
12	Tardio and Granados20	Dissection	29	5	S, P, I
13	Laurent et al21	Dissection	25	10	S, I
14	Unpublished	Dissection	12	5	S, I
		Reactive features
Cytomorphology	Hallmark Cells	Follicular Hyperplasia	Sinus Histiocytosis	Paracortical Hyperplasia	Eosinophils
Oval, lobated, anaplastic	Yes	Yes	Yes	Yes	Yes
Oval	No	Yes	No	Yes	Yes
Oval, lobated	Yes	Yes	No	No	Yes
Oval	No	Yes	Yes	No	Yes
Oval	No	Yes	Yes	Yes	Yes
Oval, anaplastic	Yes	Yes	Yes	No	Yes
Oval, lobated	Yes	Yes	Yes	No	Yes
Oval, lobated	No	Yes	Yes	Yes	Yes
Lobated	No	Yes	Yes	No	No
Oval, lobated	No	Yes	No	No	Yes
Oval, lobated	Yes	No	No	No	Yes
Lobated, anaplastic	Yes	Yes	Yes	Yes	No
Lobated	Yes	Yes	No	No	Yes
Oval	No	Yes	Yes	Yes	Yes

D indicates diffuse; I, interfollicular; NSHL-like, nodular sclerosis Hodgkin lymphoma-like; HL-like, Hodgkin lymphoma-like (excludes NSHL-like); LN, Lymph node; P, perifollicular; S, sinusoidal.