TABLE 4.
Pathologic Features of LNI of Patients With BI-ALCL (n = 14)
N (%) | |
---|---|
Specimen type | |
Excisional biopsy | 7 (50.0) |
Lymph node dissection | 6 (42.9) |
Needle biopsy | 1 (7.1) |
Lymph node maximum dimension (n = 13) | |
Median (mm) | 23.6 |
Range (mm) | 8.9-51 |
Lymphoma features | |
Pattern of infiltration | |
Sinusoidal | 13 (92.9) |
Perifollicular | 7 (50.0) |
Interfollicular | 12 (85.7) |
Diffuse | 4 (28.6) |
Hodgkin lymphoma like* | 2 (14.3) |
Tumor burden | |
Median (%) | 25 |
Range (%) | 1-95 |
Cytomorphology | |
Oval | 13 (92.9) |
Lobated | 9 (64.3) |
Anaplastic | 5 (35.7) |
Hallmark cells | 7 (50.0) |
Lymph node necrosis | 5 (35.7) |
Non-neoplastic features | |
Follicular hyperplasia | 13 (92.9) |
Paracortical hyperplasia | 5 (35.7) |
Sinus histiocytosis | 8 (57.1) |
Eosinophils | 13 (92.9) |
Refringent material | 1 (7.1) |
Foamy histiocytes | 1 (7.1) |
Hodgkin lymphoma-like: 1 nodular sclerosis HL-like, 1 mixed cellularity HL-like.