TABLE 4.
Pathologic Features of LNI of Patients With BI-ALCL (n = 14)
| N (%) | |
|---|---|
| Specimen type | |
| Excisional biopsy | 7 (50.0) |
| Lymph node dissection | 6 (42.9) |
| Needle biopsy | 1 (7.1) |
| Lymph node maximum dimension (n = 13) | |
| Median (mm) | 23.6 |
| Range (mm) | 8.9-51 |
| Lymphoma features | |
| Pattern of infiltration | |
| Sinusoidal | 13 (92.9) |
| Perifollicular | 7 (50.0) |
| Interfollicular | 12 (85.7) |
| Diffuse | 4 (28.6) |
| Hodgkin lymphoma like* | 2 (14.3) |
| Tumor burden | |
| Median (%) | 25 |
| Range (%) | 1-95 |
| Cytomorphology | |
| Oval | 13 (92.9) |
| Lobated | 9 (64.3) |
| Anaplastic | 5 (35.7) |
| Hallmark cells | 7 (50.0) |
| Lymph node necrosis | 5 (35.7) |
| Non-neoplastic features | |
| Follicular hyperplasia | 13 (92.9) |
| Paracortical hyperplasia | 5 (35.7) |
| Sinus histiocytosis | 8 (57.1) |
| Eosinophils | 13 (92.9) |
| Refringent material | 1 (7.1) |
| Foamy histiocytes | 1 (7.1) |
Hodgkin lymphoma-like: 1 nodular sclerosis HL-like, 1 mixed cellularity HL-like.