Table 1.
Characteristics of the studies (n=6) included in the meta-analysis
| Study | Zhou et al | Chen et al | Tang et al | Wang et al | Huang et al | Wu et al |
|---|---|---|---|---|---|---|
| Study year | 2020 | 2020 | 2020 | 2020 | 2020 | 2020 |
| Study location | Wuhan, China | Wuhan, China | Wuhan, China | Wuhan, China | Wuhan, China | Wuhan, China |
| Study type | Retrospective cohort | Retrospective cohort | Cross-sectional study | Retrospective cohort | Prospective Cohort | Retrospective Cohort |
| Sample size | 191 (Cases 54, Controls 137) | 274 (Cases 113, Controls 161) | 183 (Cases 21, Controls 162) | 138 (Cases 36, controls 102) | 41 (Cases 13, Controls 28) | 201 (Cases 84, Controls 117) |
| Median age | 56 (46-67) | 62 (44-70) | 54 (44-62) | 56 (42-68) | 49 (41-58) | 51 (43-60) |
| Female | 72 (38%) | 103(38%) | 85 (46.44%) | 63 (45.7%) | 11 (27%) | 73 (36.3%) |
| Composite end point | All-cause mortality (in-hospital) | All-cause mortality (in-hospital) | All-cause mortality (in-hospital) | ICU admission | ICU admission | ARDS (WHO definition) |
| Median D-dimer level, case and control | Cases- 5.2 (1.5-21.1) Controls- 0.6 (0.3-1.0) | Cases- 4.6 (1.3-21.0) Controls- 0.6 (0.3-1.3) | Cases- 2.12 (0.77-5.27) Controls- 0.61 (0.35-1.29) | Cases- 4.14 (1.91-13.24) Controls- 1.66 (1.01-2.85) | Cases- 2.4 (0.6-14.4) Controls- 0.5 (0.3-0.8) | Cases- 1.16 (0.46-5.37) Controls- 0.52 (0.21-0.94) |