Table 3.

Ribavirin dose adjustment based on renal function.

Ribavirin formulations	GFR ≥ 50 ml/min	GFR 30 to 50 ml/min	GFR < 30 ml/min	ESRD1 patients with hemodialysis
Rebetol® capsule/solution and Ribasphere® capsule	No dosage adjustment is required	Contraindicated	Contraindicated	Contraindicated
Copegus®, Moderiba®, and Ribasphere® tablets	No dosage adjustment is required	Alternate 200 mg and 400 mg every other day	200 mg once daily	200 mg once daily

¹End stage renal disease