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. 2020 Sep 18;2(12):e667–e676. doi: 10.1016/S2589-7500(20)30192-8

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© 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license

Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.

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Overview of AI-assisted drug repurposing for COVID-19

AI algorithms can be used for drug repurposing, which is a rapid and cost-effective way to discover new therapy options for emerging diseases. Reproduced by permission of Cleveland Clinic Center for Medical Art and Photography. AI=artificial intelligence. PARP1=poly-ADP-ribose polymerase 1. NR3C1=nuclear receptor subfamily 3 group C member 1. AAK1=AP2-associated protein kinase 1. MTNR1A=melatonin receptor 1A. TMPRSS2=transmembrane serine protease 2. ACE2=angiotensin I converting enzyme 2. NRP1=neuropilin 1. NSP14=non-structural protein 14.