Figure 2.

AI for drug repurposing in an integrative context

AI approaches can greatly accelerate drug repurposing by incorporating biological knowledge (eg, human interactome, organelles, tissues, and organs). The cogs indicate computer programs and algorithms. Red and black circles represent neurons in deep neural networks. Red indicates that this neuron carries important information from the biological systems. Green and blue people indicate different subgroups that might have different responses to the treatment. The downward arrows show that AI algorithms can use the information from multi-level biological systems and drug development pipelines to build more powerful models. The left panel shows the biological systems and the right panel shows the drug development pipeline AI=artificial intelligence.