Table 2. Nutritional parameters, fat pad mass and adiposity index.
Groupa | Mean food intake (g/day) | Drink ingested (mL/day) | Perigonadal fat (% BW) | Retroperitoneal fat (% BW) | Visceral fat (% BW) | Adiposity index (%) |
---|---|---|---|---|---|---|
STD-C | 21.69 ± 1.43 | 36.03 ± 1.19 | 1.04 ± 0.15 | 1.09 ± 0.07 | 0.99 ± 0.11 | 3.12 ± 0.03 |
STD+7.5 (13 cRA) | 19.95 ± 1.38 | 35.76 ± 1.9 | 0.81 ± 0.03 | 0.85 ± 0.06 | 0.77 ± 0.04 | 2.43 ± 0.02 |
STD+15 (13 cRA) | 16.94 ± 1.70 | 34.92 ± 1.1 | 0.72 ± 0.01 | 0.75 ± 0.04 | 0.68 ± 0.02 | 2.15 ± 0.02 |
HFD-C | 18.45 ± 1.31 | 28.99 ± 1.35 | 1.28 ± 0.05 | 1.45 ± 0.23 | 1.39 ± 0.07 | 4.12 ± 0.05 |
HFD+7.5 (13 cRA) | 19.73 ± 2.07 | 30.37 ± 0.85 | 1.37 ± 0.01 | 1.55 ± 0.11 | 1.49 ± 0.03 | 4.41 ± 0.05° |
HFD+15 (13 cRA) | 21.90 ± 1.80 | 30.02 ± 0.69 | 1.52 ± 0.02° | 1.72 ± 0.03° | 1.65 ± 0.06° | 4.89 ± 0.06*°°° |
aRats were fed either STD or HFD for 9 weeks ad libitum. 13 cRA was orally administered to rats via a gastric tube in two different concentrations (7.5 mg/kg, 15 mg/kg) during 30 days. Visceral, perigonadal and retroperitoneal adipose tissue was removed and weighed during animal sacrifice. Adiposity index (%) was calculated as: ([retroperitoneal fat (g) + visceral fat (g) + epigonadal fat (g)] / [body weight (g)]) × 100 and expressed as adiposity percentage. Number of rats per group: 6.
*Statistically significantly different in relation to STD-C (* P≤0.05). ⁰Statistically significantly different in relation to STD+15 RA (⁰⁰ P≤0.01, ⁰⁰⁰ P<0.001). Data are expressed as mean ± SEM. Data were analysed using Kruskal-Wallis ANOVA (STATISTICA 13 StatSoft, Tulsa, OK, USA).