Table 3.
Multivariate Cox proportional analysis of disease-free survival and baseline characteristics.
| HR (95% CI) | P-value | |
|---|---|---|
| UISS, othera vs. T3 low | 1.83 (1.19–2.81) | 0.0059 |
| Neutrophil-to-lymphocyte ratio, < 3 vs. ≥3 | 1.61 (1.15–2.26) | 0.0060 |
| Fuhrman grade, 1 and 2 vs. 3 and 4 | 0.69 (0.52–0.90) | 0.0070 |
| Treatment, sunitinib vs. placebo | 0.74 (0.58–0.96) | 0.0204 |
| Platelet-to-lymphocyte ratio, <140 vs. ≥140 | 0.79 (0.61–1.03) | 0.0809 |
| Age, 65 vs. 65 years | 1.26 (0.95–1.66) | 0.1109 |
| Sex, female vs. male | 1.18 (0.87–1.60) | 0.2924 |
| BMI, <25 vs. ≥25 | 0.88 (0.68–1.15) | 0.3532 |
| Baseline ECOG PS, 0 vs. >0 | 0.91 (0.67–1.23) | 0.5309 |
| UISS, T3 high vs. T3 low | 1.07 (0.79–1.45) | 0.6457 |
a
T4, N0 or NX, M0, any Fuhrman’s grade, and any ECOG status or Any T, N1–2, M0, any Fuhrman’s grade, and any ECOG status.
Abbreviations: BMI, body mass index; CI, confidence interval.