Table 2.
Comparison of clinical and demographic baseline characteristic between Alzheimer’s disease dementia patients with and without seizures
| AD dementia patients with seizures (n = 287) | AD dementia patients without seizures (n = 8840) | Total (n = 9127) | P value | |
|---|---|---|---|---|
| Mean age ± SD, years | 71.1 ± 10.9 | 75.2 ± 9.8 | 75.1 ± 9.9 | < 0.0011 |
| Female: male, No | 154: 133 | 4986: 3854 | 5140: 3987 | 0.362 |
| Mean age of onset ± SD, years | 64.7 ± 11.2 | 70.4 ± 9.9 | 70.2 ± 10.0 | < 0.0011 |
| Mean disease duration ± SD, years | 6.3 ± 4.1 | 4.8 ± 3.3 | 4.8 ± 3.4 | < 0.0011 |
| Mean MMSE score ± SD | 16.6 ± 8.6 | 19.6 ± 6.6 | 19.5 ± 6.7 | < 0.0013 |
| Mean CDR-SB score ± SD | 9.3 ± 5.8 | 6.8 ± 4.3 | 6.8 ± 4.4 | < 0.0013 |
AD Alzheimer’s disease, SD standard deviation, MMSE mini mental state examination, CDR-SB clinical dementia rating-sum of boxes
1p Value is derived from Mann–Whitney U test
2p Value is derived from Fisher’s exact test
3After adjustment for age and disease duration in a generalized linear model