Table 4.
Sensitivity analyses showing different testing windows for HBV, HCV, and TB for new users of biologic therapies, N (%)
HBV | HCV | TB | Composite measure | |
---|---|---|---|---|
Primary analysis* | 7,731 (28.8) | 10,854 (40.5) | 7,117 (29.7) | 4,157 (15.5) |
Sensitivity analysis 1† | 8,794 (32.8) | 12,110 (45.2) | 9,813 (40.9) | 4,919 (18.4) |
Sensitivity analysis 2** | 9,143 (34.1) | 12,527 (46.7) | 15,231 (63.4) | 6,675 (24.9) |
Primary analysis: HBV (Hepatitis B virus) and HCV (Hepatitis C virus) testing were required to have occurred at any time prior to the index date; TB (tuberculosis) testing was required in the 12 months prior to the index date.
Sensitivity analysis 1: for HBV and HCV, this window was defined as any time prior to the index date through 60 days after the index date; for TB testing, this window was defined as 12 months prior to the index date through 60 days after the index date.
Sensitivity analysis 2: for all tests we searched all available data, including both before and after the index date.