Table 1.

Proteins discussed in this review

APC Transporter:	- Amino acid Polyamine organo-Cation Transporter - 12 transmembrane domains - proton-substrate symporter - 26 family members (mostly amino acid transporters)
MFS Transporter:	- Major Facilitator Superfamily Transporter - 12 transmembrane domains - members include hexose transporters
Pil1/Lsp1:	- eisosome localized BAR domain proteins - oligomerize on the plasma membrane into large complexes that form the basic scaffold for the eisosomes - assembly is regulated by phosphorylation
Nce102:	- eisosome localized tetraspan protein (4 transmembrane domains) - possibly involved in the membrane domain organization at the eisosome
Slm1/2:	- soluble, eisosome localized proteins - contain BAR domain and PH domain (binds PI4,5P2) - interacts and activates TORC2
Pma1:	- P2-type ATPase that exports protons - most abundant plasma membrane protein - one of the largest ATP consumers in yeast
Rsp5:	- member of the NEDD4 family of ubiquitin ligases - major ubiquitin ligase acting at the plasma membrane and endo-lysosomal system
ARTs:	- Arrestin-Related Trafficking (ART) adaptors, also known as alpha-arrestins - function in recruitment of Rsp5 to APC transporters - regulated by phosphorylation and ubiquitination
TORC2:	- Tor Complex 2, composed of Tor2, Lst8, Avo1, Avo2, Avo3, Bit61 - localizes to the plasma membrane - is activated by environmental stress that impact cell integrity - regulates lipid synthesis, actin cytoskeleton and endocytosis
AMPK:	- AMP-dependent Kinase, trimeric complex composed of the kinase subunit Snf1, the subunit Snf4 and either Sip1, Sip2 or Gal83 - is activated by low cellular energy levels - major regulator of the cell’s metabolism