Table 2.
ECG data.
| Total population (n = 112) | Group 1 No Therapy (n = 19) | Group 2 HCQ (n = 40) | Group 3 HCQ + AZT (n = 53) | p-value | |
|---|---|---|---|---|---|
| ECG data | |||||
| Heart rate, bpm | 76.5 ± 15.4 | 76.5 ± 19.4 | 76.1 ± 15.3 | 76.7 ± 13.2 | 0.981 |
| Rhythm | |||||
| Sinus rhythm | 103 (92) | 17 (90) | 39 (98) | 47 (89) | 0.274 |
| Atrial fibrillation | 9 (8) | 2 (11) | 1 (3) | 6 (11) | 0.274 |
| PQ interval, ms | 172.1 ± 39.6 | 167.9 ± 31.3 | 169.2 ± 286 | 175.8 ± 48.9 | 0.683 |
| QRS, ms | 99.3 ± 23.3 | 102.3 ± 20.2 | 102.1 ± 20.4 | 108 ± 47.1 | 0.670 |
| LBBB, n (%) | 5 (5) | 1 (25) | 3 (8) | 1 (2) | 0.424 |
| RBBB, n (%) | 6 (5) | 0 (0) | 3 (8) | 3 (6) | 0.485 |
| Incomplete RBBB, n (%) | 7 (6) | 1 (5) | 3 (8) | 3 (6) | 0.919 |
| Incomplete LBBB, n (%) | 3 (3) | 0 (0) | 0 (0) | 3 (6) | 0.180 |
| QT interval, ms | 400.5 ± 41.5 | 385.7 ± 40.3 | 394.8 ± 36.4 | 401.4 ± 29.6 | 0.221 |
| QTc, Bazett, ms | 442.1 ± 28.8 | 424.4 ± 24.9 | 436.3 ± 28.4 | 452.8 ± 26.4 | <0.001⁎, ⁎⁎ |
| QTc prolonged, n (%) | 55 (49) | 2 (11) | 16 (40) | 37 (70) | <0.001 |
| QTc > 500 ms, n (%) | 4 (4) | 0 (0) | 0 (0) | 4 (8) | 0.099 |
| T peak/T end, ms | 94.5 ± 23.2 | 86.5 ± 23.9 | 95.5 ± 25.1 | 94.5 ± 23.3 | 0.210 |
LBBB, left bundle branch block; RBBB, right bundle branch block.
⁎
p < 0.05 Group 3 vs. Group 1
⁎⁎
p < 0.05 Group 3 vs. Group 2.