Table 2.
Entire Cohort (n = 1601) | mRS 0–2 Favorable (n = 1074) | mRS 3–6 Unfavorable (n = 527) | P-value* | |
---|---|---|---|---|
White matter hyperintensity volume (median [IQR]), Missing, n | 3.13 [1.02 – 7.50] 316 | 2.50 [0.77 – 6.44] 167 | 4.44 [1.93 – 9.53] 149 | < 0.0001 |
LVO, n (%) | 353 (22.0%) | 200 (18.6%) | 153 (29.0%) | < 0.0001 |
Anterior (IM1M2) LVO, n (%) | 241 (15.1%) | 131 (12.2%) | 110 (20.9%) | < 0.0001 |
TOAST Subtype, n (%) | 0.1998 | |||
Cardioembolism | 490 (30.6%) | 315 (29.3%) | 175 (33.2%) | |
Large-artery atherosclerosis | 385 (24.0%) | 259 (24.1%) | 126 (23.9%) | |
Small vessel occlusion | 259 (16.2%) | 189 (17.6%) | 70 (13.3%) | |
Stroke of undetermined etiology | 412 (25.7%) | 275 (25.6%) | 137 (26.0%) | |
Stroke of other determined etiology | 55 (3.4%) | 36 (3.4%) | 19 (3.6%) | |
NIHSS at admission (median [IQR]) Missing, n | 3[1–6] 73 | 2[1–4] 36 | 4[2–10] 37 | < 0.0001 |
NIHSS at admission, n (%) | < 0.0001 | |||
No stroke symptoms (0) | 309 (20.2%) | 246 (23.7%) | 63 (12.9%) | |
Minor stroke (1–4) | 728 (47.6%) | 536 (51.6%) | 192 (39.2%) | |
Moderate stroke (5–15) | 384 (25.1%) | 223 (21.5%) | 161 (32.9%) | |
Moderate/severe stroke (16–20) | 59 (3.9%) | 21 (2.0%) | 38 (7.8%) | |
Severe stroke (21–42) | 48 (3.1%) | 12 (1.2%) | 36 (7.3%) | |
Missing | 73 (4.6%) | 36 (3.4%) | 37 (7.0%) | |
Treatment, n (%) | 0.0239 | |||
IV tPA | 151 (9.4%) | 110 (10.2%) | 41 (7.8%) | |
Mechanical thrombectomy | 15 (0.9%) | 9 (0.8%) | 6 (1.1%) | |
IV tPA and mechanical thrombectomy | 24 (1.5%) | 10 (0.9%) | 14 (2.7%) | |
None | 1411 (67.0%) | 945 (88.0%) | 466 (88.4%) | |
IV tPA Treatment, n (%) | 175 (10.9%) | 120 (11.2%) | 55 (10.4%) | 0.7332 |
TICI reperfusion score among thrombectomy treatments, n (%) | 0.0074 | |||
mTCI 0 | 6 (15.4%) | 0 (0.0%) | 6 (30.0%) | |
mTICI 1 | 0 (0.0%) | 0 (0.0%) | 0 (0.0%) | |
mTICI 2A | 2 (5.1%) | 0 (0.0%) | 2 (10.0%) | |
mTICI 2B | 14 (35.9%) | 7 (36.8%) | 7 (35.0%) | |
mTICI 3 | 17 (43.6%) | 12 (63.2%) | 5 (25.0%) | |
Secondary intracerebral hemorrhage, n (%) | 130 (8.1%) | 75 (7.0%) | 55 (10.4%) | 0.0195 |
P-value: Continuous variables were compared using Wilcoxon rank-sum tests and categorical variables were compared using Fisher’s exact tests.