Table 2.

Cox Logistic regression analysis for the risk of hard cardiac events.

	Univariate
	HR	95% CI	p value
Age	1.8	0.8–7.4	0.08
NYHA Class (≥III)	2.3	1.4–3.8	0.001
HS Troponine I	1.05	1.2–3.02	0.017
NT-proBNP	1.4	1.2–4.5	0.004
AL/TTR	1.18	0.6–2.3	0.6
LV EF	1.74	0.87–3.5	0.12
LV EDVi	1.5	0.61–3.9	0.36
LV mass index	1.9	0.98–3.8	0.06
RVEF (%)	0.97	0.95–0.99	0.013
RV EDVi	1.16	0.46–2.9	0.73
LA maximal Volume	1.01	1–1.01	0.0008
AEF	0.94	0.91–0.97	0.0009
AEF ≤ 14%	4.1	2.08–8.1	<0.0001
Model with AEF (continuous)	Multivariate
	HR	95% CI	p value
NYHA Class (≥III)	2.4	1.2–4.7	0.012
NT-proBNP
RVEF (%)
LA maximal Volume
AEF	0.9	0.9–0.98	0.005
Model with AEF ≤ 14% (dichotomic)	Multivariate
	HR	95% CI	p value
NYHA Class (≥III)	2.9	1.5–5.7	0.002
NT-proBNP
RVEF (%)
LA maximal Volume
AEF ≤ 14%	4.0	2.0–7.9	<0.0001

LV, left ventricle; RV, right ventricle; EDVi, end-diastolic volume index; EF, ejection fraction; LA, left atrium; AEF, atrial ejection fraction, HS, High-sensitivity.

Only parameters with p value <0.05 at univariate were included in multivariate analysis.