Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Inhibitory effect of synthesized trans-tephrostachin 4a and derivatives 4b – 4e.
| Compound | Vmax | Km (μM) | Ki (μM) | Inhibition type |
|---|---|---|---|---|
| Without Inhibitor | 0.34 ± 0.01 | 173.5 ± 17.8 | _____ | _____ |
| 4a | 0.13 ± 0.08 | 234.3.0 ± 35.0 | 29.3 ± 7.2 | Mixed inhibition |
| 4b | 0.34 ± 0.01 | 240 ± 23.6 | 206.3 ± 12 | Competitive inhibition |
| 4c | 0.14 ± 0.1 | 205.5 ± 34.7 | 46.42 ± 9.5 | Mixed inhibition |
| 4d | 0.15 ± 0.01 | 247.6 ± 36.7 | 8.3 ± 1.7 | Mixed inhibition |
| 4e | 0.36 ± 0.2 | 265.2 ± 37.18 | 197.62 ± 10.1 | Competitive inhibition |
