Table 2.
Clinical data and medical history (n=1019 People with multiple sclerosis), stratified by age.
| <=55 years | >55 years | |
|---|---|---|
| n (%) | 512 (50%) | 507 (50%) |
| CIS | 10 (2) | 8 (2) |
| RRMS | 408 (80) | 245 (48) |
| SPMS | 66 (13) | 155 (31) |
| PPMS | 26 (5) | 92 (18) |
| Unknown to participant | 2 (0.4) | 7 (1) |
| Patient-determined disease step (PDSS) score, median (1st quartile, 3rd quartile) | 2 (0, 4) | 4 (2, 5) |
| Taken DMT within past year Yes No Don't know |
417 (81) 88 (17) 7 (1) |
331 (65) 166 (33) 10 (2) |
| DMTsa: Glatiramer acetate Interferon beta-1 Peginterferon beta-1a Fingolimod Siponimod Dimethyl fumarate Diroximel fumarate Teriflunomide Cladribine Natalizumab Rituximab Ocrelizumab Alemtuzumab Otherb |
35 (7) 21 (4) 3 (0.6) 58 (11) 3 (0.6) 52 (10) 0 20 (4) 6 (1) 44 (9) 21 (4) 134 (26) 7 (1) 5 (1) |
48 (9) 23 (5) 4 (0.8) 23 (5) 5 (1) 35 (7) 3 (0.6) 25 (5) 4 (0.8) 23 (5) 17 (3) 104 (21) 0 5 (0.9) |
| MS relapse in last month Yes No Don't Know |
46 (9) 415 (81) 51 (10) |
34 (7) 440 (87) 33 (7) |
| Hospitalized due to MS in 2019 Yes No Don't know |
24 (5) 156 (30) 3 (0.6) |
13 (3) 136 (27) 0 |
| Ever hospitalized due to MS Yes No Don't Know |
183 (36) 322 (63) 7 (1) |
149 (29) 350 (69) 8 (2) |
| Needed steroids in the last month Yes No Don't Know |
27 (5) 480 (94) 5 (1) |
26 (5) 475 (94) 6 (1) |
| In-person neurologist visit in last 6 months Yes No Don't Know |
396 (77) 109 (21) 7 (1) |
374 (74) 131 (26) 2 (0.4) |
| Medical history/comorbidities: Asthma Cancer (current) Depression Diabetes Heart disease Hypertension Lung disease Smoke cigarettes Avg. cigarettes/day |
83 (16) 6 (1) 229 (45) 18 (4) 11 (2) 81 (16) 14 (3) 41 (8) 12 |
44 (9) 29 (6) 193 (38) 35 (7) 43 (8) 183 (36) 28 (6) 23 (5) 12 |
a104 participants <=55 years of age did not have DMT data available. 184 participants >55 years of age did not have DMT data available. bIncludes ibudilast, mycophenolate mofetil and cyclophosphamide.