Table. Clinical Characteristics at Baseline.
| Characteristic | No. (%) | ||||
|---|---|---|---|---|---|
| All | Age group | ||||
| <65 y | 65-74 y | 75-84 y | ≥85 y | ||
| No. | 30 801 | 5107 | 5792 | 10 985 | 8917 |
| Age, mean (SD), y | 76.8 (13.3)a | 53.4 (10.2) | 70.6 (2.9) | 80.3 (2.8) | 89.9 (3.7) |
| Men | 13 507 (43.9) | 2794 (54.7) | 2942 (50.8) | 4865 (44.3) | 2906 (32.6) |
| eGFR, mean (SD), mL/min/1.73 m2 | 26.2 (3.4) | 25.6 (3.8) | 26.3 (3.4) | 26.5 (3.3) | 26.2 (3.3) |
| Albuminuria, missing | 2978 (9.7) | 270 (5.3) | 382 (6.6) | 995 (9.1) | 1331 (14.9) |
| A1b | 13 318 (43.2) | 1093 (21.4) | 2190 (37.8) | 5278 (48) | 4757 (53.3) |
| A2b | 7091 (23) | 1026 (20.1) | 1464 (25.3) | 2736 (24.9) | 1865 (20.9) |
| A3b | 7414 (24.1) | 2718 (53.2) | 1756 (30.3) | 1976 (18) | 964 (10.8) |
| Diabetes | 13 906 (45.1) | 2758 (54) | 3403 (58.8) | 5007 (45.6) | 2738 (30.7) |
| CVD | 18 063 (58.6) | 1807 (35.4) | 3188 (55) | 6880 (62.6) | 6188 (69.4) |
| MI | 3692 (12) | 360 (7) | 684 (11.8) | 1514 (13.8) | 1134 (12.7) |
| CHF | 13 073 (42.4) | 1132 (22.2) | 2211 (38.2) | 4957 (45.1) | 4773 (53.5) |
| Stroke or TIA | 7865 (25.5) | 716 (14) | 1301 (22.5) | 2999 (27.3) | 2849 (32) |
| Peripheral vascular disease | 2285 (7.4) | 258 (5.1) | 535 (9.2) | 920 (8.4) | 572 (6.4) |
Abbreviations: CHF, congestive heart failure; CVD, cardiovascular disease; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; TIA, transient ischemic attack.
Median (interquartile range) age was 80 (70-86) years.
A1, A2, and A3 are categories of proteinuria, which were calculated according to the following KDIGO (Kidney Disease Improving Global Outcomes) recommendations: A1 = albuminuria less than 30 mg/24 hours, or proteinuria less than 150 mg/24 hours, or albumin-creatinine ratio (ACR) less than 3 mg/mmol (<30 mg/g), or protein-creatinine ratio (PCR) less than 15 mg/mmol (<150 mg/g), or protein reagent strip negative to trace value. A2 = albuminuria 30 to 300 mg/24 hours, or proteinuria 150 to 500 mg/24 hours, or ACR 3 to 30 mg/mmol (30-300 mg/g), or PCR 15 to 50 mg/mmol (150-500 mg/g), or protein reagent strip trace to positive value. A3 = albuminuria greater than 300 mg/24 hours, or proteinuria greater than 500 mg/24 hours, or ACR greater than 30 mg/mmol (>300 mg/g), or PCR greater than 50 mg/mmol (>500 mg/g), or protein reagent strip positive value or greater.