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. 2020 Sep 18;21:401. doi: 10.1186/s12882-020-02042-x

Table 2.

Light (LM) and electron microscopic (EM) findings in renal biopsies in 11 patients with HIV and membranous nephropathy

Patient Diagnoses Total glomeruli* GS (%) IFTA (%) FSGS Arteriosclerosis EM Deposit location EM MN stage FPE (%)
1 MN 7 0 < 5 0 Normal/minimal NA NA NA
2 HIVAN; MN; mild DN 42 43 90 Collapsing Severe Mes; SEpi (segmental); IM II-III 60–70 (variable)
3 MN; TIN 38 5 10 0 Mild SEpi; IM II-IV 100
4 MN; TIN 39 3 0 Moderate Mes; SEpi; IM II-III 50 (variable)
5 MN 32 9 5 0 Mild SEpi I-II 100
6 MN 46 42 75 NOS Severe SEpi; IM II-III 100
7 MN 25 12 10 0 Mild SEpi I-II 100
8 MN 28 0 5 0 Moderate SEpi II 100
9 MN 14 36 50 0 Moderate SEpi III 100
10 MN; LLN 28 0 10 0 Mild Mes (rare); SEndo (rare); SEpi (segmental) I 60–70 (variable)
11 MN 45 13 30 NOS Severe Mes; SEpi IV 80%

Abbreviations: GS: glomerulosclerosis; IFTA: interstitial fibrosis and tubular atrophy; FSGS: focal and segmental glomerulosclerosis; FPE: foot process effacement; MN: membranous nephropathy; TIN: tubulointerstitial nephritis; LLN: lupus-like nephropathy; DN: diabetic nephropathy; Mes.: mesangial; SEpi.: subepithelial (diffuse unless otherwise specified); SEndo.: subendothelial; IM: intramembranous. Deposits are considered diffuse unless otherwise specified. *Describes total glomeruli sampled for LM, EM, and IF