Table 2.
Distributions of DPP-4 activity in kidney
| Diagnosis | Podocyte | Bowman’s capsule | Proximal tubule | Distal tubule | Interstitial tissue | others | |
|---|---|---|---|---|---|---|---|
| case 1 | Minor glomerular abnormalitya | – | +/− | + | – | – | |
| case 2 | Minor glomerular abnormality | – | +/− | ++ | – | – | |
| case 3 | Minor glomerular abnormality | – | + | ++ | – | – | |
| case 4 | ANCA-RNa | – | + | ++ | – | – | crescent ++ |
| case 5 | ANCA-RN | – | + | + | – | – | crescent + |
| case 6 | ANCA-RN with DPP-4i | – | – | + | – | – | |
| case 7 | ANCA-RN | – | +/− | + | – | – | crescent - |
| case 8 | FSGSa | + | + | ++ | – | – | |
| case 9 | FSGS | + | + | ++ | – | – | |
| case 10 | FSGS | + | + | ++ | – | – | |
| case 11 | FSGS | +/− | + | ++ | – | – | |
| case 12 | FSGS | + | +/− | + | – | – | |
| case 13 | FSGS | + | +/− | ++ | – | – | |
| case 14 | FSGS | + | + | ++ | – | – | |
| case 15 | Nephrosclerosisa | – | – | ++ | – | – | |
| case 16 | DN w/o DPP-4iab | + | +/− | ++ | – | – | nodule + |
| case 17 | DN w/o DPP-4ib | + | +/− | + | – | – | nodule + |
| case 18 | DN w/o DPP-4ib | +/− | + | ++ | – | – | nodule + |
| case 19 | DN with DPP-4ib | +/− | +/− | + | – | – | |
| case 20 | DN with DPP-4i | + | + | ++ | – | – | |
| case 21 | DN with DPP-4i | +/− | +/− | + | – | – | |
| case 22 | DN with DPP-4i | +/− | +/− | + | – | – | |
| case 23 | DN with DPP-4i | – | – | + | – | – | |
| case 24 | DN with DPP-4i | + | +/− | + | – | – | |
| case 25 | DN with DPP-4ib | – | + | – | – | – | |
| case 26 | DN with DPP-4ib | – | – | +/− | – | – | |
| case 27 | DN with DPP-4ib | + | +/− | +/− | – | – | nodule + |
ANCA-RN ANCA-related nephritis, FSGS focal segmental glomerular sclerosis, DN w/o DPP-4i diabetic nephropathy without DPP-4 inhibitor treatment, DN with DPP-4i diabetic nephropathy treated with DPP-4 inhibitor
DPP-4 activity was evaluated in -, +/−, +, ++