Fig. 4.
A. Effect of compounds on cell metabolic activity; 105 BxPC-3 cells were exposed to 10 μM hit compounds for 24 h, and the effect on MTS staining for each time point measured by absorbance at 492 nm. Background media absorbance was subtracted from all values and expressed as a proportion of untreated cells. Data is expressed as mean ± SEM; data do not show any significant differences by two-way ANOVA; n = 3 separate experiments. B: Effect of compounds on cell metabolic activity of Panc-1 cells; 105 Panc-1 cells were exposed to 10 μM hit compounds for 24 h, and the effect on MTS staining for each time point measured by absorbance at 492 nm. Background absorbance of media was subtracted from all values and expressed as a proportion of untreated cells. Data is expressed as mean ± SEM; data do not show any significant differences by two-way ANOVA; n = 3 separate experiments.