Fig. 5.

The invasive capacity of BxPC-3 and Panc-1 cells treated with 10 μM of compound 4 for 48 h. A) Invasion of BxPC-3 treated cells towards 10% FBS as a chemoattractant. B) Invasion of Panc-1 treated cells towards 10% FBS as a chemoattractant. C) Graphical representation of the data showing a comparison between the invasions of BxPC-3 and Panc-1 treated cells and controls. The total number of invading cells in the lower chamber was determined by counting the number of cells in 5 different fields, at 100x magnification. Error bars represent the mean ± standard error from three independent invasion experiments (n = 3; each containing average of 5 picture fields selected at x100 total magnification).