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. 2020 Sep 16;8:e9949. doi: 10.7717/peerj.9949

Table 2. Correlation between clinicopathological characters and expressions of Galectin-3 and Galectin-9.

Character n Expression of Galectin-3 Median H-score (quartile) P Expression of Galectin-9 Median H-score (quartile) P
0–120 121–300 0–100 101–300
Gender
Male 195 157 (80.5%) 38 (19.5%) 0(0–80) 0.390 110 (56.4%) 85 (43.6%) 90(40–180) 0.984
Female 52 44 (84.6%) 8 (15.4%) 0(0–90) 28 (53.8%) 24 (46.2%) 90(30–180)
Age
≤55ys 127 100 (78.7%) 27 (21.3%) 0(0–120) 0.110 74 (58.3%) 53 (41.7%) 90(20–180) 0.643
>55ys 120 101 (84.2%) 19 (15.8%) 0(0–60) 64 (53.3%) 56 (46.7%) 90(60–180)
HBV/HCV
HBV positive 158 123 (77.8%) 35 (22.2%) 0(0–120) 0.052 90 (57.0%) 68 (43.0%) 90(30–180) 0.817
HCV positive 45 41 (91.1%) 4 (8.9%) 0(0–0) 25 (55.6%) 20 (44.4%) 90(40–180)
Negative 44 37 (84.1%) 7 (15.9%) 0(0–60) 23 (52.3%) 21 (47.7%) 90(40–180)
Number of tumor
Single 183 151 (82.5%) 32 (17.5%) 0(0–80) 0.061 99 (54.1%) 84 (45.9%) 90(50–180) 0.561
Multiple 64 50 (78.1%) 14 (21.9%) 7.5(0-112.5) 39 (60.9%) 25 (39.1%) 90(5–180)
Tumor size
≤5 cm 137 117 (85.4%) 20 (14.6%) 0(0–80) 0.334 99 (54.1%) 84 (45.9%) 90(60–180) 0.427
>5 cm 110 84 (74.6%) 26 (23.4%) 0(0–120) 39 (60.9%) 25 (39.1%) 90(0–180)
Differentiation
Poor 75 59 (78.7%) 16 (21.3%) 15(0–100) 0.016 49 (65.3%) 26 (37.4%) 80(0–180) 0.002
Moderate/well 172 142 (82.6%) 30 (17.4%) 0(0–75) 89 (51.7%) 83 (48.3%) 90(60–180)
Lymph-vascular invasion
No 138 117 (84.8%) 21 (15.2%) 0(0–60) 0.049 71 (51.4%) 67 (48.6%) 90(67.5-180) 0.012
Yes 109 84 (77.1%) 25 (22.8%) 0(0–110) 67 (61.5%) 42 (38.5%) 90(0–180)
Cirrhosis
No 99 72 (72.7%) 27 (27.3%) 0(0–150) 0.040 53 (53.5%) 46 (46.5%) 90(50–180) 0.560
Yes 148 129 (87.2%) 19 (17.8%) 0(0–60) 85 (57.4%) 63 (42.6%) 90(22.5-180)
AJCC clinical stage
I 109 95(87.2%) 14 (12.8%) 0(0–60) 0.242 55 (50.5%) 54 (49.5%) 100(70–180) 0.106
II 100 74 (74.0%) 26 (26.0%) 0(0–140) 61 (61.0%) 39 (39.0%) 90(20–180)
III 38 32 (84.2%) 6 (15.8%) 0(0–90) 22 (57.9%) 16 (42.1%) 85(0–180)