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Ex vivo Permeation Parameters of the Optimized AKBA-Loaded SNVs and AKBA Dispersion
| Formula | *t lag (h) | *Jss (µg cm−2 hr−1) | *KP (cm hr−1) | ER |
|---|---|---|---|---|
| AKBA dispersion | 0.63±0.05 | 7.84±0.45 | 0.0078±0.15 | – |
| F7 | 0.16±0.02 | 26.21±1.53 | 0.0262±0.12 | 3.34 |
Notes: *Each value represents mean ± SD (n = 3). F7: the optimized AKBA-loaded SNVs.
Abbreviations: t lag, lag time; Jss, steady state flux; KP, permeability coefficient; ER, enhancement ratio.
