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. 2020 Sep 15;13:9135–9145. doi: 10.2147/OTT.S266846

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© 2020 Zhu et al.

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CLDN8 expression levels in the specimens and cell lines. (A and B) Western blot and qPCR analysis of ccRCC cell lines and normal cell lines. (C) The CLDN8 mRNA expression in ccRCC tissues and paired normal tissues in 20 paired clinical samples. (D) Representative adjacent normal renal tissue staining and ccRCC tissue staining are shown. (E) Four representative images of CLDN8 expression were interpreted by immunohistochemistry as no, weak, moderate, and strong. (F) The average scores of immunohistochemical staining were shown (***p<0.001).