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. 2020 Sep 15;13:9135–9145. doi: 10.2147/OTT.S266846

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© 2020 Zhu et al.

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CLDN8 regulates ccRCC cells in vitro. (A and B) Overexpression of CLDN8 inhibited the migration and invasion of ccRCC cells. (C) The effect of overexpression of CLDN8 on the EMT pathway was detected by Western blot. (D and E) Overexpression of CLDN8 inhibited the proliferation of ccRCC cells. (F) The effect of overexpression of CLDN8 on the AKT pathway was detected by Western blot (*p<0.05, **p<0.01, ***p<0.001).