Table 2.
Univariate and Multivariate Analyses in TCGA Database
| Variables | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
| HR (95% CI) | p-value | HR (95% CI) | p-value | |
| CLDN8 (High vs Low) | 0.538 (0.369,0.784) | 0.001 | 0.674 (0.460,0.986) | 0.042 |
| Age (>60 vs ≤60) | 1.751 (1.282,2.391) | <0.001 | 1.636 (1.195,2.240) | 0.002 |
| Gender (Male vs Female) | 0.940 (0.686,1.288) | 0.701 | ||
| Grade (G3+G4 vs G1+G2) | 2.588 (1.834,3.652) | <0.001 | 1.647 (1.143,2.373) | 0.007 |
| T (T3+T4 vs T1+T2) | 3.040 (2.233,4.139) | <0.001 | 1.799 (1.137,2.847) | 0.012 |
| M (M1 vs M0) | 4.258 (3.109,5.832) | <0.001 | 2.373 (1.628,3.459) | <0.001 |
| Stage (III+IV vs I+II) | 3.661 (2.655,5.048) | <0.001 | 1.974 (1.331,2.929) | 0.001 |