Table 2.
Effect of the crude extract and fraction 12 on hematological parameters.
| PH treatments | Doses (mg/kg) | WBC (×109/l) | RBC (×1012/l) | PL (%) | MPV (fl) | PDW | HGB (g/dl) | HCT (%) | MCV (fl) | MCHC (Pg) | MCHC (g/dl) | DIRBC (%) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neutral control | 0 | 7.6 ± 1.1∗ | 9.10 ± 0.5∗ | 0.45 ± 0.05 | 6.60 ± 0.20 | 14.20 ± 0.10 | 14.3 ± 1.60∗ | 48.3 ± 0.8∗ | 54.22 ± 3.40 | 15.70 ± 0.70 | 31.10 ± 0.20 | 17.70 ± 0.50 |
| Negative control | 14.10 ± 2.10 | 6.80 ± 0.40 | 0.32 ± 0.07 | 6.90 ± 0.20 | 14.50 ± 0.20 | 8.70 ± 1.20 | 32.2 ± 6.50 | 53.30 ± 3.20 | 14.80 ± 0.40 | 29.10 ± 1.20 | 18.10 ± 0.10 | |
|
| ||||||||||||
| CQ | 5 | 9.10 ± 0.60∗ | 8.20 ± 0.43∗ | 0.39 ± 0.06 | 6.70 ± 0.10 | 14.10 ± 0.20 | 10.60 ± 1.20∗ | 44.10 ± 0.40∗ | 54.10 ± 2.40 | 15.00 ± 0.40 | 31.40 ± 0.30 | 17.90 ± 0.20 |
|
| ||||||||||||
| Crude extract | 125 | 10.5 ± 1.03∗ | 8.30 ± 0.23∗ | 0.37 ± 0.03 | 7.00 ± 0.10 | 14.3 ± 0.20 | 12.10 ± 0.20∗ | 41.2 ± 0.9∗ | 52.11 ± 0.50 | 14.70 ± 0.60 | 29.00 ± 0.20 | 17.70 ± 0.41 |
| 250 | 11.4 ± 0.20∗ | 8.68 ± 0.22∗ | 0.50 ± 0.13 | 6.90 ± 0.20 | 14.90 ± 0.30 | 11.60 ± 0.3∗ | 40.11 ± 2.1∗ | 52.00 ± 0.30 | 13.90 ± 0.90 | 27.23 ± 0.37 | 17.60 ± 0.40 | |
| 500 | 10.40 ± 0.23∗ | 8.70 ± 0.40∗ | 0.31 ± 0.05 | 7.00 ± 0.20 | 14.60 ± 0.20 | 13.40 ± 0.40∗ | 42.7 ± 5.40∗ | 52.20 ± 0.70 | 14.90 ± 0.50 | 28.80 ± 0.23 | 17.20 ± 0.22 | |
|
| ||||||||||||
| Fraction 12 | 62.5 | 11.12 ± 0.41∗ | 8.05 ± 0.06∗ | 0.39 ± 0.32 | 6.96 ± 0.06 | 14.18 ± 0.32 | 9.36 ± 0.15∗ | 42.61 ± 0.31∗ | 53.89 ± 0.12 | 13.64 ± 0.62 | 29.06 ± 0.08 | 17.83 ± 0.14 |
| 125 | 10.32 ± 0.11∗ | 8.21 ± 0.07∗ | 0.43 ± 0.28 | 6.53 ± 0.02 | 14.13 ± 0.14 | 9.86 ± 0.31∗ | 43.13 ± 0.75∗ | 54.17 ± 0.58 | 14.93 ± 0.13 | 30.02 ± 0.31 | 17.94 ± 0.74 | |
HCT: hematocrit; HGB: hemoglobin; MCHC: mean corpuscular hemoglobin concentration; MCV: mean corpuscular volume; PL: platelets; DIRBC: distribution index of red blood cells; MPV: mean platelet volume.