Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Purine-based Hsp90 inhibitors – A) PU-3 was the first fully synthetic Hsp90 inhibitor and first of the purine-based class. B) BIIB021 and BIIB028 modify the N-7 and N-9 positions of the purine base. C-E) PU-H71, MPC-3100, Debio0932 each add a unique 1,3-benzodioxole moiety to the N-8 position via a thioether bond and a variable substituent to the N-9 position.
