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Resorcinol-containing Hsp90 inhibitors – All inhibitors in this class contain a resorcinol moiety. A-C) Luminespib, ganetespib, and onalespib add two substituents to the resorcinol ring at ortho-positions to the hydroxyl groups; one is an isopropanol moiety and the other is unique to each compound. D) KW-2478 adds three substituents to the resorcinol moiety – two ortho and one meta to the hydroxyl groups.
